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Amlodipine 5

Category
Antihypertensive

Composition :
Amlodipine 5 : Each tablet contains Amlodipine besylate 6.935 mg equivalent to amlodipine 5 mg


Indication :
Amlodipine is indicated for the first line treatment of hypertension and can be used as the sole agent to control blood pressure in the majority of patients.
Patients not adequately controlled on a single antihypertensive agent many benefit from the addition of amlodipine, which has been used in combination with a thiazide diuretic, β-adrenoreceptor blocking agent, or an angiotensinconverting enzym inhibitor. Amlodipine is indicated for the first line treatment of myocardial ischemia, whether due to fixed obstruction (stable angina) and / or vasospasm / vasoconstriction (Prinzmetal's or variant angina) of coronary vasculature.
Amlodipine may be used where the clinical presentation suggests a possible vasospastic / vasoconstrictive component but where vasospatic / vasconstrictive has not been confirmed.
Amlodipine may be used alone, as monotherapy, or in combination with other antianginal drugs in patients with angina that is refractory to Nitrates and or adequate doses of beta blockers.

Dosage and Administration :
For hypertension the usual initial dose is  5 mg Amlodipine once daily which may be increased to a maximun dose of 10 mg dependinf on the individual patient’s response and severity. Small, fragile, or eldery individuals, or patients, with hepatic insuffciency may be started on 2.5 mg once daily and this dose may be used when adding Amlodipine to other antihypertensive therapy.
Majority of hypertensive patients with 5 mg/day the dose may not necessarily be increased. For those who need higher dose, Amlodipine can be increased to 7.5 mg/day with maximum dose of 10mg/day.
The recommended dose for chronic stable or vasospatic angina is 5-10 mg, with the lower dose suggested in the elderly and in patients with hepatic insufficiency.
No dose adjusment of amlodipine is required upon concomitant administration of Thiazide diuretics, β blockers, and angiotensin-coverting enzym inhibitors.
Use in Children : No experience is available on use of Amlodipine in children.

Contraindications :
Amlodipine is contraindicated in patients with a know sensitivity to dihydropyridines.

Presentation :
Amlodipine®5 : Box, 3 strips @ 10 tablets

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