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Carsive

Category
Antihypertensive

CARSIVE®

Category :
Calcium Antagonists

Composition :
Nicardipine HCl

Indication :
Hypertensive emergencies. Emergency treatment  of acute hypertensive crisis during surgery.

Dosage :
Emergency treatment of acute HTN crisis during surgery 2-10 mcg/kg/min IV drip infusion until desired BP value is reached & adjusted thereafter w/ monitoring to maintain BP. For rapid BP reduction 10-30 mcg/kg IV inj. Hypertensive emergencies 0.5-6 mcg/kg/min IV drip infusion at rate of 0.5 mcg/kg/min until desired BP value is reached & adjusted thereafter w/ monitoring to maintain BP.

Contraindications :
Suspected incomplete hemostasis following intracranial hemmorhage; elevated intracranial pressure at acute stage of cerebral stroke.

Special Precautions :
Abrupt w/drawal. Hepatic or renal dysfunction, aortic stenosis. Elderly. Childn. Pregnancy & lactation.

Adverse Drug Reactions :
Paralytic ileus, hypoxemia, angina, dyspnea, thrombocytopenia, hepatic dysfunction, jaundice, tachycardia, palpitations, facial flushing, general malaise; BUN or creatinine elevation; nausea, vomiting. Headache, fever, decrease urine vol, rigors, backpain, serum K elevation.

Drug Interactions :
Saquinavir, ritonavir, other hypotensives, β-blockers, fentanyl, digoxin, phenytoin, nitroglycerine, muscle relaxants, rifampicin, immunosuppressants, dantrolene Na, tandospiron citrate.

Presentation :
Inj (amp) 10 mg/10 mL x 10's

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